A Cross-Sectional Study of Risk Factors for Gastrointestinal Carriage of Klebsiella Pneumoniae and Bacterial Genomic Diversity

EasyChair Preprint 14958

Abstract

This study investigates the risk factors associated with gastrointestinal carriage of Klebsiella pneumoniae, a significant pathogen known for its role in healthcare-associated infections. Through a cross-sectional analysis, we assessed the prevalence of K. pneumoniae in gastrointestinal samples from diverse patient populations, alongside comprehensive genomic sequencing to evaluate bacterial diversity. Our findings reveal a correlation between specific demographic factors, antibiotic exposure, and the likelihood of K. pneumoniae carriage. The genomic analysis highlights a range of clonal lineages, underscoring the complexity of transmission dynamics. By identifying critical risk factors, this research contributes to understanding the epidemiology of K. pneumoniae, informing strategies for infection control and antibiotic stewardship in clinical settings. The implications for public health and the necessity for ongoing surveillance are discussed, emphasizing the need for targeted interventions to mitigate the risks associated with this opportunistic pathogen.

Keyphrases: Klebsiella, Pathogen., Pneumoniae, gastrointestinal, interventions, mitigate, opportunistic, risks associated, targeted

@booklet{EasyChair:14958,
  author    = {Anthony Collins},
  title     = {A Cross-Sectional Study of Risk Factors for Gastrointestinal Carriage of Klebsiella Pneumoniae and Bacterial Genomic Diversity},
  howpublished = {EasyChair Preprint 14958},
  year      = {EasyChair, 2024}}